Christian Yelich, David Hamilton, Jake Bauers and Luis Lara hit home runs for the host Milwaukee Brewers, who tied a franchise record for runs in a game in a 22-0 win over the Seattle Mariners on Tuesday night.

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The Brewers also tied a modern-day record in MLB for the largest margin of victory in a shutout. Yelich’s three-run homer with two outs in the fifth capped off the first big inning for Milwaukee. Hamilton, who went 3-for-5 with a career-high four RBIs, matched Yelich’s feat an inning later. Bauers followed up with a two-run shot later in the frame.

It was the biggest explosion since the Brewers defeated the Toronto Blue Jays 22-2 on Aug. 28, 1992. Kyle Harrison (10-3) shined on the mound for the Brewers, punching out eight in five shutout innings. He gave up two hits and walked two.

For Seattle, the 22-run margin surpassed its previous worst defeat, a 21-1 loss to Houston on Sept. 8, 2019. Bryce Miller (4-7) had a stretch of nine straight retired in the middle of his outing but struggled on either side of that, giving up seven hits and six runs (five earned) in 4 2/3 innings. Brendan Donovan and Dominic Canzone each had a double for the Mariners, who only mustered five hits.

Dodgers 7, Rockies 6

Shohei Ohtani homered, Teoscar Hernandez tripled and doubled and Los Angeles held off a late surge to beat Colorado in Denver.

It was Ohtani’s third home run in the first two games of the series. Tommy Edman doubled twice and Freddie Freeman also had two hits. Tanner Scott, elevated to closer with Edwin Diaz on the injured list, picked up his 17th save. Catcher Hunter Feduccia left the game in the seventh due to a reported illness.

Willi Castro homered and scored three runs and TJ Rumfield and Jake McCarthy had two hits for each Colorado, which has dropped its first two games following a 5-4 road trip.

Angels 3, Astros 1

George Klassen twirled a career-best seven shutout innings in his fifth career start, and visiting Los Angeles recorded two-out RBIs in three successive innings to defeat Houston.

Klassen (2-1) surrendered four baserunners — one hit and three walks — and recorded a career-best seven strikeouts. Josh Lowe belted a solo shot, Zach Neto hit an RBI double Nolan Schanuel added an RBI single.

Cam Smith ended the Angels’ shutout bid with a homer, his 17th, leading off the eighth against reliever Jose Fermin. Astros starter Cristian Javier (1-4) gave up two runs on five hits in four innings.

Padres 5,
Mets 2

Fernando Tatis Jr. homered twice and Robbie Ray tossed six solid innings for visiting San Diego, which beat New York in the middle game of a three-game series.

Tatis also saved a grand slam, robbing Francisco Lindor with a leaping catch at the right field wall. Manny Machado homered and Ty France had an RBI single. Ray (11-7) surrendered one run on three hits. Mason Miller (31st save) tossed a 1-2-3 ninth.

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Luis Torrens and Luis Robert Jr. homered for the Mets, whose four-game winning streak was snapped. Torrens and Bo Bichette finished with two hits each. Mets rookie Zac Thornton (3-4) took the loss after allowing three runs on six hits over five innings.

Phillies 6,
Marlins 4

Alec Bohm and Bryson Stott each drove in two runs to guide Philadelphia to a victory over visiting Miami.

Philadelphia won its fifth straight despite a subpar outing from Zack Wheeler, who walked four in five innings while allowing two runs and two hits with seven strikeouts. Luis Arraez (three hits) and Justin Crawford (two hits, RBI) also made key contributions.

Griffin Conine had two hits, including a homer, and scored twice for Miami. The Marlins, who used six pitchers in a planned bullpen game, have dropped four of their last six.

Pirates 4,
Tigers 1

Braxton Ashcraft gave up one run over eight innings and Oneil Cruz homered in his return to the lineup to help host Pittsburgh secure a victory over Detroit.

Ashcraft (13-5) struck out four, did not issue a walk and gave up five hits on an efficient 80 pitches to help the Pirates lock up a needed win. Ashcraft’s gem followed his one-run, complete-game masterpiece last Thursday against the Marlins.

The only blemish on Ashcraft’s start came in the fifth when rookie Brett Callahan hit his first major league home run — a 393-foot blast to right field — to break a scoreless stalemate. Callahan had two of the Tigers’ five hits.

Red Sox 9,
Diamondbacks 4

Adley Rutschman and Mickey Gasper each hit a solo home run to help Boston defeat the visiting Arizona. Rutschman went 2-for-4 with three RBIs and Gasper collected two hits and two walks and drove in two runs.

The Red Sox had 13 hits in the game and have scored 20 runs while winning the first two games in the three-game series. Rutschman’s home run in the third inning was his ninth of the season, but his first since the Baltimore Orioles traded him to the Red Sox on Aug. 3.

Gabriel Moreno hit a grand slam off Ranger Suarez in the third inning for the Diamondbacks, who have lost their last three games. Arizona’s Ketel Marte missed his second straight game. He traveled to Phoenix to get an MRI exam on his balky left knee one day after failing to report to Fenway Park.

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